Drugs & Vitamins

Imiglucerase Active Ingredients: Imiglucerase Representative Names: Cerezyme What is imiglucerase injection? What should I tell my health care provider before I take this medicine? How should I use this medicine? What if I miss a dose? What drug(s) may interact with imiglucerase? What side effects may I notice from receiving imiglucerase? What should I watch for while taking imiglucerase? Where can I keep my medicine? What is imiglucerase injection? (Back to top) IMIGLUCERASE (Cerezyme®) replaces a naturally occuring enzyme that is missing in patients with Gaucher's disease. This enzyme helps with fat breakdown in the body. It helps keep blood contents at normal levels, and it may help prevent your liver or spleen from getting big. Generic imiglucerase injections are not yet available. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •high pressure in the blood vessels of the lungs (known as pulmonary hypertension) •an unusual or allergic reaction to imiglucerase, other medicines, foods, dyes, or preservatives •pregnant or are trying to get pregnant •breast-feeding How should I use this medicine? (Back to top) Imiglucerase is for infusion into a vein. It is given in a hospital or health clinic setting by a trained health-care professional. Most people receive their medication at least once every 2 weeks. However, the dose for each person is adjusted just for them. What if I miss a dose? (Back to top) Try not to miss an appointment. Call your prescriber or health care professional for advice if you miss a dose. What drug(s) may interact with imiglucerase? (Back to top) There are no known interactions between imiglucerase and other medicines. What side effects may I notice from receiving imiglucerase? (Back to top) Side effects that you should report to your prescriber or health care professional as soon as possible: During the infusion, let your prescriber know if any of the following occur: •discomfort in the chest •difficulty breathing or shortness of breath •itching or skin rash •feeling of dizziness or faintness •palpitations or racing heartbeat Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •backache •diarrhea •headache •fever or chills •nausea, vomiting •stomach discomfort •swelling, pain or itching at the injection site •tired feeling What should I watch for while taking imiglucerase? (Back to top) Tell your prescriber or health care professional if imiglucerase does not improve your symptoms or if it makes your symptoms worse. Where can I keep my medicine? (Back to top) This medication is stored in the refrigerator, but since someone will give it to you, you will not have to store your doses at home. Last Updated:11/04/2001 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.